Included on KINE are:


(1).
Statement by Dr. Pierre Grondin
1.08

(2).
Interview with Mrs. Murphy



TRANSCRIPT: (SEQ 1) GRODIN: "THE MOST IMPORTANT PROBLEM NOW" DR. GRODIN SAID, WAS "WHETHER THE HEART OF A 38-YEAR OLD MAN WHOSE OWN HEART HAD SWOLLEN TO TWO TO THREE TIMES NORMAL SIZE"




Initials



Script is copyright Reuters Limited. All rights reserved

Background: 1ST ADD 3RD LD HEART MONTREAL (086A) X X X PRESSURE."
THE WEARY-LOOKING DR. GRONDIN, A VETERAN OF OPEN HEART SURGERY, TOLD AN 11 AM BRIEFING THAT MRS. RONDEAU'S DEATH WAS CERTIFIED AT 11:30 PM THURSDAY, AND THE OPERATION TO TRANSFER HER HEART TO MURPHY BEGAN ONE MINUTE LATER.

"WE HAD THREE POSSIBLE DONORS," DR. GRONDIN, 43, TOLD NEWSMEN. MRS. RONDEAU WAS SELECTED BECAUSE OF "A HISTO (TISSUE) COMPATIBILITY THAT WAS VERY GOOD" WITH THAT OF MURPHY.

MRS. RONDEAU'S DEATH, OF MASSIVE CEREBRAL HEMORRHAGE, WAS CERTIFIED AT 11:29 PM EDT. THE TRANSPLANT OPERATION BEGAN ONE MINUTE LATER, AND LASTED UNTIL 3:30 AM.

"THE OPERATION WENT SMOOTHLY," DR. GRONDIN, WHO WAS GARBED IN GREEN SURGICAL CAP AND GOWN, REMARKED QUIETLY. THE ONLY DIFFICULTY CAME, HE SAID, DURING A 45-MINUTE "CARDIO-PULMONARY BYPASS PERIOD" WHEN ADEQUATE CIRCULATORY PRESSURE HAD TO BE MAINTAINED.

MURPHY BECAME THE WORLD'S 18TH HEART TRANSPLANT PATIENT. A 19TH TRANSPLANT OPERATION TOOK PLACE SHORTLY AFTER IN ARGENTINA. SEVEN HEART RECIPIENTS HAVE SURVIVED SO FAR.

DR. GRONDIN SAID HE HOPED TO ALLOW MURPHY'S WIFE TO VISIT HIM TOMORROW.

PICKUP 6TH PGH 019A MURPHY'S
X1155AEB
2ND ADD 3RD LD HEART MONTREAL (086A) X X TOMORROW.

RAVAGED BY DEBILITATING HEART AILMENTS OVER A 15-YEAR PERIOD, MURPHY'S OTHER MAJOR ORGANS, INCLUDING LIVER AND KIDNEYS, WERE ALSO SWOLLEN. DOCTORS HOPED MORE CORRECT CIRCULATION WOULD RESTORE THEM TO NORMAL SIZE.

MURPHY HAD BEEN UNDERGOING PREPARATORY CARE SINCE HE BECAME A POTENTIAL HEART RECIPIENT MORE THAN TWO MONTHS AGO, DR. GRONDIN SAID. THE INSTITUTE TEAM HAS BEEN PLANNING FOR TRANSPLANT FOR FIVE MONTHS.

DR. GRONDIN SAID HE USED "THE TECHNIQUE THAT HAS BECOME STANDARD BY NOW," ONE PERFECTED BY DR. NORMAN SHUMWAY OF PALO ALTO, CALIF. DR. GRONDIN SAID AS PART OF HIS PERSONAL PREPARATION HE HAD TO "STOOD OVER THE RIGHT SHOULDER" OF DR. DENTON COOLEY WHILE COOLEY PERFORMED THE WORLD'S 15TH TRANSPLANT AT HOUSTON, TEX. RECENTLY.

DR. GRONDIN DEVELOPED A 27-MAN TEAM, INCLUDING 12 SURGEONS, TO CARRY OUT THE TRANSPLANTATION. MURPHY'S CASE CAME TO THEIR ATTENTION BECAUSE HIS CONDITION WAS "VERY SEVERE AND IRREVERSIBLE, TERMINAL IN FACT." CONFINED TO HIS HOME IN RECENT YEARS, HE WAS ABLE TO DO LITTLE MORE THAN OCCASIONALLY SIT UP IN A CHAIR.

A NEWSMAN AT THE BRIEFING REMINDED DR. GRONDIN THAT THE DOCTOR HAD "EXPRESSED DOUBTS" ABOUT THE FEASIBILITY OF HEART TRANSPLANTS IN JANUARY. DR. GRONDIN, IN TURN, REMINDED THE REPORTER THAT HE HAD ADDED THAT IF TRANSPLANT RECIPIENTS WERE STILL ALIVE BY MAY OR JUNE, HE WOULD FEEL MUCH MORE EAST ABOUT THEM.

PICKUP AS BEFORE 6TH PGH 086A: MURPHY'S
INXETYIN 2ND PGH HEART 102A XX SIZE."
ONLY ONE MALE RECIPIENT OF A FEMALE HEART, OF WHICH THERE ARE FIVE KNOWN INSTANCES, S